金银花和山银花在《中国药典》2015年版中的性味与归经、功能与主治、用法与用量上无差异，自《中国药典》2005年版将金银花和山银花分列，纷争不断。通过查阅国内外文献，从金银花和山银花的用药沿革、鉴别、化学成分、药理作用及质量控制等方面入手，探讨金银花和山银花的异同及质量控制的关键问题；为解决金银花和山银花的分合问题，促进中药材产业的发展奠定基础。

More and more disputes have happened to confront continuously since the separation of Lonicera Japonicae Flos and Lonicerae Flos in the 2005 edition of Chinese Pharmacopoeia, however, there are no differences in the properties, flavors, and channel tropism, functions of curing, usage and dosage in the 2015 edition of Chinese Pharmacopoeia. By consulting literatures on the medical history, identification, chemical composition, pharmacological action, quality control, and other aspects of Lonicera Japonicae Flos and Lonicerae Flos at home and abroad in recent years, we explore the similarities and differences between Lonicera Japonicae Flos and Lonicerae Flos, and the key issues of quality control in order to solve the problem of the combination and separation between them, which can lay a foundation for promoting the development of traditional Chinese medicinal materials industry.

国家自然科学基金资助项目（81703824）；湖南省自然科学基金资助项目（2017JJ3236）；湖南省教育厅一般项目（17C1209）；中药成药性与制剂制备湖南省重点实验室资助项目（201705）