[关键词]
[摘要]
目的 研究光果甘草Glycyrrhiza glabra根中的化学成分。方法 利用硅胶柱色谱及半制备HPLC进行分离纯化,通过理化性质及现代波谱技术对分离得到的化合物进行结构鉴定。结果 从光果甘草醋酸乙酯部位分离得到10个异黄烷类化合物,分别鉴定为光甘草素T(1)、光甘草定(2)、glyasperin C(3)、甘草西定(4)、异甘草黄酮醇(5)、甘草异黄酮A(6)、甘草异黄酮B(7)、半甘草异黄酮B(8)、芒柄花素(9)、甘草素(10)。结论 化合物1为新的异黄烷类化合物,化合物3~6为首次从该植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from the roots of Glycyrrhiza glabra. Methods Compounds were separated and purified by silica gel and preparative HPLC. The structures were identified by physicochemical properties and spectral analyses. Results Ten isoflavanes were isolated and identified as glabrene T (1), glabridin (2), glyasperin C (3), licoricidin (4), isolicoflavonol (5), licoisoflavone A (6), licoisoflavone B (7), semilicoisoflavone B (8), formononetin (9), and liquiritigenin (10), respectively. Conclusion Compound 1 is a new isoflavane. Compounds 3-6 are isolated from this plant for the first time.
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[基金项目]
四川省科技厅应用基础研究(面上)项目(2017JY0192)