目的 研究野艾蒿Artemisia lavandulaefolia地上部分的化学成分。方法 采用多种柱色谱技术进行分离和纯化，根据波谱数据鉴定化合物的结构。结果 从野艾蒿95%乙醇提取物中分离得到11个化合物，分别鉴定为（4R，5R，7R，10R）-4-羟基-桉烷-2，11-二烯-1-酮（1）、5-表-桉烷-4（15）-烯-1β，6β-二醇（2）、桉烷-4（15）-烯-1β，6α-二醇（3）、3-氧代-桉烷-1，4，11（13）-三烯-12-羧酸甲酯（4）、11β，13-二氢珊塔玛内酯（5）、anthemidin（6）、东莨菪素（7）、丹皮酚（8）、咖啡酸乙酯（9）、espeletone（10）、（1R^*，2S^*，3S^*，4S^*）-薄荷烷-1，2，3，4-四醇（11）。结论 化合物1为新化合物，命名为野艾蒿酮A；化合物2～11均为首次从该植物中分离得到。

Objective To study the chemical constituents from the aerial parts of Artemisia lavandulaefolia.Methods The constituents were isolated and purified by various column chromatographic techniques, and their structures were identified by spectroscopic analysis.Results Eleven compounds were isolated from 95% ethanol aqueous extract of A. lavandulaefolia and the structures were identified as (4R, 5R, 7R, 10R)-4-hydroxy-eudesma-2, 11-dien-1-one (1), 5-epi-eudesma-4(15)-ene-1β, 6β-diol (2), eudesma-4(15)-ene-1β, 6α-diol (3), methyl 3-oxo-eudesma-1, 4, 11(13)-trien-12-oate (4), 11β, 13-dihydrosantamarin (5), anthemidin (6), scopoletin (7), paeonol (8), ethyl caffeate (9), espeletone (10), and (1R^*, 2S^*, 3S^*, 4S^*)-mentha-1, 2, 3, 4-tetrol (11).Conclusion Compound 1 is a new compound named artemilavanone A, and compounds 2—11 are isolated from this plant for the first time.

国家自然科学基金资助项目（81773611，21402212）；云南省教育厅科学研究基金指导性项目（2017zDX156）