[关键词]
[摘要]
目的 建立铁屑生品的X射线衍射(XRD)Fourier指纹图谱分析方法,探讨不同炮制方法对铁屑药材品质的影响。方法 采用粉末XRD技术对矿物药铁屑生品进行分析,测定其XRD Fourier指纹图谱,并对6种炮制品的XRD Fourier图谱叠加进行比较,运用K值法测定了不同炮制品中Fe3O4质量分数。结果 初步建立了11批铁屑生品的XRD Fourier指纹图谱共有模式,确立了10个共有峰,其中3号峰和6号峰分别为Fe3O4和FeO的特征峰;生品和6种炮制品在共有峰的数目和强度上存在一定差异,与Fe3O4质量分数变化规律一致。结论 XRD Fourier指纹图谱分析法可用于铁屑药材的鉴定与分析,为铁屑生品的质量评价及炮制方法的筛选提供依据。
[Key word]
[Abstract]
Objective To establish the Fourier transform X-ray diffraction (XRD) fingerprint of Farina Ferrum and to explore the effect of different processing methods on the quality of medicinal materials. Methods The technology of powder XRD was used for analyzing Farina Ferrum, and the XRD Fourier fingerprints were also determined. Then the XRD Fourier patterns of six kinds of processed products were compared by superimposed way, and the K value method was used to determine the content of Fe3O4 in different processed products. Results XRD characteristic fingerprint of 11 batches of Farina Ferrum was established. Ten common peaks were characterized, in which the third and sixth peaks were from Fe3O4 and FeO, respectively. There were some differences in the number and intensity of peaks among raw materials and six kinds of processed products, which were consistent with the variation of mass fraction of Fe3O4. Conclusion The XRD fingerprint could be used for the appraisal and the analysis of Farina Ferrum, and the basis could be provided for the quality evaluation of Farina Ferrum and the option of processing methods.
[中图分类号]
[基金项目]
国家十二五科技支撑计划(2012BAI27B07);研究生创新项目(CX2017SZ084)