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[摘要]
糖尿病肾病(DKD)是糖尿病最严重的微血管并发症之一,也是导致出现终末期肾脏病的主要原因。现代医家在把握其病因病机的基础上,着眼于葛根素的现代药理研究,证实葛根素对DKD患者的血糖、蛋白尿、肾功能、血流动力学状况、血脂、血压等多项指标有明显的改善作用。综述葛根素治疗DKD的研究进展,以期为葛根素的进一步开发研究和临床应用提供参考。
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[Abstract]
Diabetic nephropathy (diabetic kidney disease, DKD) is one of the most serious microvascular complications of diabetes which is also the leading cause of end-stage renal disease (ESRD). On the basis of grasping its etiology and pathogenesis, modern physicians focus on the modern pharmacological studies of puerarin and prove that puerarin has significant improvement on multiple indicators of blood glucose, proteinuria, renal function, hemodynamics, blood lipids, and blood pressure in patients with DKD. This article reviews puerarin in the above aspects of the therapeutic effect The research progress of puerarin on diabetic nephropathy is reviewed in order to provide reference for the research and clinical application of puerarin.
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