[关键词]
[摘要]
研究中药药效物质基础对于阐明中药作用机制和提高中药质量标准具有关键的作用,中药药效物质基础研究方法主要包括:血清药物化学、谱效相关和药动学-药效学(PK-PD)模型研究等方面。通过查阅相关文献,对中药药效物质基础的主要研究方法进行综述,为阐明中药复方的药效物质基础提供参考。
[Key word]
[Abstract]
Studies on the effective material basis of Chinese materia medica (CMM), which is critical for clarifying the mechanism of action and control quality. The main research methods on the effective material basis of CMM were reviewed through consulting relevant literature in this paper. It mainly includes the serum pharmaceutical chemistry, spectrum-effect and PK/PD model research.
[中图分类号]
[基金项目]
安徽中医药大学科研项目(2018zrzd14);安徽省自然科学基金项目(1708085MH196);安徽省卫生计生委中医药科研课题(2016zy03);国家中医药管理局临床中药学重点学科建设项目(国中医药人教发[2012]32号);2015年中医药部门公共卫生专项基金项目“中药炮制技术传承基地建设”