柑橘属中药陈皮Citri Reticulatae Pericarpium、枳实Aurantii Fructus Immaturus、枳壳Aurantii Fructus均为常用理气药，但三者在功效、主治方面各有侧重。从本草考证、化学成分、药理作用3个方面对芸香科柑橘属中药陈皮、枳实、枳壳进行总结、比较与分析，进一步基于质量标志物（Q-marker）的核心概念并结合药效、药性、药动学的研究进行分析，对其质量标志物进行预测，为建立和完善药材质量标准提供理论依据。

Citri Reticulatae Pericarpium, Aurantii Fructus Immaturus, and Aurantii Fructus belong to the traditional Chinese medicine derived from citrus and are commonly used for regulating vital (Qi in Chinese). But these three are different in the function, efficacy and therapeutic. Based on the concept of Q-marker and the combination of pharmacodynamics, pharmacological and pharmacokinetic studies, their quality markers were predicted. The prediction study provides a theoretical basis for establishing and improving the quality standard of the medicinal materials.

国家自然科学基金重点项目（81430096）；国家中药标准化项目（ZYBZH-Y-JX-27）