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[摘要]
目的 研究粉团蔷薇Rosa multiflora var.cathayensis根的化学成分。方法 采用硅胶、HPLC等柱色谱方法进行分离纯化,并根据化合物的理化性质和光谱分析进行结构鉴定。结果 从粉团蔷薇根的醋酸乙酯及二氯甲烷提取部位中分离得到了9个三萜类化合物,分别鉴定为粉团蔷薇甲苷(1)、阿江榄仁尼酸(2)、1β-羟基蔷薇酸(3)、阿江榄仁亭(4)、构莓苷F1(5)、蔷薇酸(6)、委陵菜酸(7)、千花木酸(8)、野蔷薇苷(9)。结论 化合物1为新化合物,命名为粉团蔷薇甲苷;所有化合物均为首次从粉团蔷薇根中分离得到。
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[Abstract]
Objective To study the chemical from the roots of Rosa multiflora var.cathayensis. Methods The silica gel column chromatography was used to separate the chemical constituents from the roots of Rosa multiflora var.cathayensis. HPLC was used to analyze its purity, chemical and spectroscopy methods were used to determine their structures. Results Nine constituents were isolated and identified as multifloside A (1), arjunic acid (2), 1β-hydroxyeuscaphic acid (3), arjunetin (4), kaji-ichigoside F1 (5), euscaphic acid (6), tormentic acid (7), myrianthic acid (8), and rosamultin (9). Conclusion Compound 1 is a new compound named multifloside A; All compounds are obtained from the genus Rosa for the first time.
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[基金项目]
国家自然科学基金资助项目"壮药金樱根新颖五环三萜抗炎活性成分及效应关系的研究"(81360683);广西中药药效研究重点实验室开放项目(14-045-12)