目的 对傣药肾茶Clerodendranthus spicatus水溶性酚酸类化学成分进行研究。方法 采用大孔树脂D101、Sephadex LH-20、MCI及制备HPLC等多种色谱技术分离纯化，并根据理化性质及波谱数据鉴定其结构。结果 从肾茶中分离得到16个化合物，分别鉴定为原儿茶醛（1）、原儿茶酸（2）、3，5-二羟基苯甲醛（3）、对羟基苯甲酸（4）、对羟基苯甲醛（5）、香草酸（6）、丹参素甲酯（7）、3，5-O-二甲基没食子酸（8）、helisterculins A（9）、紫草酸（10）、紫草酸甲酯（11）、紫草酸二甲酯（12）、helisterculins B（13）、二氢咖啡酸乙酯（14）、阿魏酸（15）、二氢阿魏酸（16）。结论 化合物3、6~9、13~16均为首次从该属植物中分离得到。

Objective To investigate the water-soluble phenolic acids from Clerodendranthus spicatus of Dai medicine. Methods The chemical constituents were separated and purified by D101, Sephadex LH-20, MCI, and preparative HPLC column chromatographies. Their structures were determined by physicochemical properties and spectral data analyses. Results Sixteen constituents were isolated and elucidated as protocatechualdehyde (1), protocatechuic acid (2), 3,5-dihydroxybenzaldehyde (3), 4-hydroxybenzoic acid (4), 4-hydroxybenzaldehyde (5), vanillic acid (6), danshensu methyl ester (7), 3,5-O-dimethyl gallic acid (8), helisterculins A (9), lithospermic acid (10), methyl lithospermate (11), dimethy lithospermate (12), helisterculins B (13), ethyl dihydrocaffeate (14), ferulic acid (15), and dihydroferulic acid (16). Conclusion Compounds 3, 6-9, and 13-16 are obtained from Clerodendranthus Kudo for the first time.