[关键词]
[摘要]
“药辅合一”是中药制剂学中独特的用药理念、制药经验与哲学智慧。然而,一直存在传统经验整理不够,现代基础研究不足的缺陷。为此,阐述“药辅合一”的理论内涵与基本特点,初步总结了中药制剂中常见的“药辅合一”现象及物理化学基础,探讨“药之为辅”与“辅之为药”的设计应用规律,并结合现代研究实例分析“药辅合一”思想对中药新辅料、新技术与新制剂研究的指导价值,以期从传统经验中探寻思路,促进传统知识与现代研究的融合,推动中药制剂学的传承与创新。
[Key word]
[Abstract]
“Unification of medicines and excipients” was the particular concept of medication use, pharmaceutical experience and philosophical wisdom in Chinese materia medica (CMM) preparations. However, the traditional experience has not been fully summed up, and the modern research and application have not attracted enough attentions. In this paper, the theoretical connotation and basic characteristics of “unification of medicines and excipients” were concluded, and the common phenomena and their physical chemical basis were summarized. Then, the design and application law of “medicines as excipients” and “excipients as medicines” were discussed. What's more, we have enumerated several modern research examples and analyzed its application value in the development of new excipients, new pharmaceutical preparation technology, and new CMM preparations. We hope to explore wisdom from the traditional experience, promote the integration of traditional knowledge and modern study, and finally accelerate the inheritance and innovation of pharmaceutics of CMM.
[中图分类号]
[基金项目]
国家自然科学基金资助项目(81403115,30973952)