目的 研究乳苣Mulgedium tataricum全草石油醚部位的化学成分。方法 采用硅胶柱色谱、重结晶、制备薄层色谱和制备液相色谱等技术进行分离纯化，并经NMR等现代波谱技术进行化合物的结构鉴定。结果 从乳苣全草60%乙醇提取物的石油醚萃取部位分离得到9个化合物，分别鉴定为蒲公英甾醇（1）、伪蒲公英甾醇（2）、羽扇豆醇（3）、齐墩果-18-烯- 3β-醇（4）、β-谷甾醇（5）、齐墩果-18-烯-3-酮（6）、3β-羟基-蒲公英-20(30)-烯-28-酸（7）、豆甾醇（8）、羽扇豆酮（9）。结论 化合物3、4、6、7和9为首次从该属植物中分离得到。

Objective To isolate and identify the chemical constituents of petroleum ether soluble part of 60% aq. ethanol extracts from the whole herb of Mulgedium tataricum. Methods Separation and purification were performed on silica gel column chromatography and recrystallization, PTLC, PHPLC, and related techniques. Their chemical structures were elucidated through spectroscopic analyses (NMR). Results Nine compounds were isolated and identified as taraxasterol (1), pseudotaraxasterol (2), lupeol (3), olean-18-en-3β-ol (4), β-sitosterol (5), olean-18-en-3-one (6), 3β-hydroxy-taraxaster-20(30)-ene-28-oic acid (7), stigmasterol (8), and lupenone (9), respectively. Conclusion Compounds 3, 4, 6, 7, and 9 are separated from this plant for the first time.

国家自然科学基金资助项目（81603267）；陕西省自然科学基金资助项目（2015JQ2048）；西安交通大学新教师科研支持计划（1191320023）；中国博士后科学基金面上资助（2016M590958）