[关键词]
[摘要]
目的 对马尔康柴胡Bupleunum malconense的地上部分进行化学成分研究。方法 利用硅胶、MCI、Sephadex LH-20等柱色谱技术分离纯化,根据理化性质和波谱数据鉴定化合物的结构。结果 从马尔康柴胡地上部分乙醇提取物中分离得到11个化合物,分别鉴定为槲皮素(1)、槲皮素-3-O-α-L-呋喃阿拉伯糖苷(2)、圣草酚(3)、3',4',5,7-四羟基-3-甲氧基黄酮(4)、原儿茶酸(5)、槲皮素-3-O-α-L-鼠李糖苷(6)、山柰酚(7)、异鼠李素(8)、芦丁(9)、β-谷甾醇(10)、胡萝卜苷(11)。结论 11个化合物均为首次从该植物中分离得到,化合物3、4为首次从柴胡属植物中分离得到。
[Key word]
[Abstract]
Objective To investigate the chemical constituents in the dried acrial part of Bupleunum malconense. Methods Column chromatography, such as silica gel, MCI, and Sephadex LH-20 were used to isolate the compounds. Spectroscopic methods such as 1H-NMR and 13C-NMR were used to elucidate their structures. Results Eleven compounds were separated and identified as quercetin (1), quercetin-3-O-α-L-arabinofuranoside (2), eriodictyol (3), 3',4',5,7-tetrahydroxy-3-methoxyflavone (4), protocatechuic acid (5), quercetin-3-O-α-L-rhamnopyranoside (6), kaempferol (7), isorhanmetin (8), rutin (9), β-sitosterol (10), and daucosterol (11). Conclusion All 11 compounds are isolated from the plants in B. malconense for the first time. Compounds 3 and 4 are isolated from the plants in genus Bupleunum L. for the first time.
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[基金项目]
国家自然科学基金委青年科学基金项目(81503200)