[关键词]
[摘要]
秦艽在我国西北地区分布广泛,资源丰富,且是一种极有开发利用价值的药用植物。目前发现秦艽中主要含有环烯醚萜苷类、木脂素类、黄酮类及三萜类等化学成分。其药理研究主要集中在抗炎、镇痛、保肝、免疫抑制、降血压、抗病毒、抗肿瘤等作用方面。通过文献检索,对近20年来国内外对秦艽的化学成分和主要药理作用的研究进展进行归纳,以期为秦艽的研究开发和应用提供参考。
[Key word]
[Abstract]
Gentianae Macrophyllae Radix, widely distributed in northwest districts of China, is rich in resources, and is a kind of medicinal plants with great utilization value. From the phytochemical view, the second metabolites such as secoiridoids, iridoids, lignans, flavonoids, and triterpenoids had been reported from this species. Its pharmacological research mainly focused on the anti-inflammatory and analgesic, hepatoprotective, hypotensive, antiviral, and antineoplastic activities. The present paper reviews the phytochemistry and biological activities of Gentianae Macrophyllae Radix through accessing Web of Science and multiple databases for biomedical sciences.
[中图分类号]
[基金项目]
北京市自然科学基金(7162117);国家自然科学基金(81673618,81403152);教育部高等学校博士学科点专项科研基金(20120013130002,20130013120001);北京中医药大学研究生自主课题(2016-JYB-XS084)