[关键词]
[摘要]
目的 对西藏胡黄连Picrorhiza scrophulariiflora干燥根茎进行化学成分研究。方法 采用反复硅胶柱色谱、Sephadex LH-20柱色谱、制备薄层色谱及重结晶等手段进行分离纯化,运用波谱学方法鉴定化合物的结构。结果 从西藏胡黄连的甲醇超声提取物中分离得到10个化合物,分别为β-谷甾醇(1)、棕榈酸(2)、反式阿魏酸二十八酯(3)、3β-羟基-豆甾-5-烯-7-酮(4)、6β-羟基-豆甾-4-烯-3-酮(5)、咖啡酸甲酯(6)、原儿茶酸甲酯(7)、香草酸(8)、咖啡酸(9)、云杉苷(10)。结论 化合物2~7、9为首次从胡黄连属植物中分离得到。
[Key word]
[Abstract]
Objective To study the constituents in the roots of Picrorhiza scrophulariiflora. Methods The constituents of P. scrophulariiflora were separated and purified with chromatographic methods. The structures were elucidated by spectroscopic methods and chemical analyses. Results Ten compounds were isolated from the roots of P. scrophulariiflora and identified as β-sitosterol(1), palmitic acid(2), octacosyl trans-ferulate(3), 3β-hydroxystigmast-5-en-7-one(4), 6β-hydroxystigmast-4-en-3-one(5), caffeic acid methyl ester(6), protocatechuic acid methyl ester(7), vanillic acid(8), caffeic acid(9), and piceoside(10). Conclusion Compounds 2-7 and 9 are obtained from the plants of Picrorhiza Royle for the first time.
[中图分类号]
[基金项目]
重庆市教委科学技术研究项目(KJ1502701)