[关键词]
[摘要]
目的 研究白苞裸蒴Gymnotheca involucrata全草的化学成分。方法 利用反相硅胶柱色谱和反相制备液相色谱等手段进行分离纯化,并通过1H-、13C-NMR等波谱技术进行结构鉴定。结果 从白苞裸蒴95%乙醇提取物中分离得到10个化合物,分别鉴定为N-苯甲酰基-2-羟基-2-(4'-羟基苯基)-乙胺(1)、N-苯甲酰基-2-(3',4'-二羟基苯基)-乙胺(2)、6,9-dihydroxy-4,7-megastigmadien-3-one(3)、对羟基苯乙腈(4)、腺苷(5)、5-hydroxy-3,4-dimethy-5-pentyl-2(5H)-furanone(6)curculonone A(7)、3α-hydroxy-5,6-epoxy-7-megastigmen-9-one(8)、gymnothelignan J(9)、gymnothelignan I(10)。结论 所有化合物均为首次从白苞裸蒴中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from G. involucrata. Methods The chemical constituents of G. involucrata were isolated by different column chromatographic techniques. The structures of these compounds were identified by a comprehensive analysis of the spectroscopic data. Results Ten compounds were isolated from G. involucrata. The compounds were identified as N-benzoyl-2-hydroxy-2-(4'-hydroxy phenyl)-ethylamine (1), N-benzoyl-2-hydroxy-2-(3',4'-dihydroxy phenyl)-ethylamine (2), 6,9-dihydroxy-4,7-megastigmadien-3-one (3), 4-hydroxybenzyl cyanide (4), adenosine (5), hydroxy dihydrobovolide (5-hydroxyl-3,4-dimethy-5-pentyl-2 (5H)-furanone (6), curculonone A (7), 3α-hydroxy-5,6-epoxy-7-megastigmen-9-one (8), gymnothelignan J (9), and gymnothelignan I (10). Conclusion All the compounds are isolated from G. involucrata for the first time.
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[基金项目]
国家自然科学基金项目(21562027);江西民族传统药现代科技与产业发展协同创新中心(JXXT201402017)