目的 探究穴位贴敷联合中药离子导入治疗法对慢性阻塞性肺疾病(COPD)患者生活质量的影响。方法 选取天津医科大学总医院于2013年10月-2015年6月收治的COPD患者共120例,随机分为对照组和观察组。对照组患者给予西医基础治疗和中药内服治疗,观察组患者除给予西医基础治疗和中药内服治疗外,住院期间给予中药离子导入疗法,出院后给予止咳平喘贴穴位贴敷3周治疗后进行随访,比较两组患者的临床疗效。结果 观察组临床疗效总有效率93.3%,对照组为76.7%。观察组患者治疗后第1秒用力呼气容积(FEV1)占预计值百分比,用力肺活量(FVC)占预计值百分比和1秒钟用力呼气容积/用力肺活量(FEV1/FVC)均有显著改善(P<0.05),肺功能明显优于对照组。观察组患者咳嗽、痰量、喘息发作、紫绀、心悸临床症状较对照组患者好转更为显著,St.George'S呼吸疾病调查问卷(SGRQ)调查评分均显著低于对照组(P<0.05)。结论 中药穴位贴敷联合中药离子导入治疗能有效改善COPD患者肺功能,减轻咳嗽、呼吸困难程度,从而显著改善COPD患者的生活质量,提高临床疗效。

Objective To investigate the effects of acupoint application combined with Chinese medicine iontophoresis therapy on life quality of patients with chronic obstructive pulmonary disease(COPD). Methods The study enrolls 120 COPD patients consecutively from October 2013 to June 2015 in General Hospital, Tianjin Medical University, who were randomly divided into control group and observation group. The patients in the control group were treated with basic treatment and oral administration of Chinese materia medica(CMM), while the patients in the observation group were treated with transdermal import therapy in acute attack and point application therapy in remittent stage, besides basic treatment. Following up after discharge the patients were given Zhike Pingchuan Patch in acupoint application for 3 weeks of treatment. Then the patients in the two groups were compared. Results The clinical efficacy rate in the observation group was 93.3%, while 76.7% in the control group. The FEV1, FVC, and FEV1/FVC percentages of estimated value for patients after treatment in the observation group were obviously improved, respectively(P<0.05). The pulmonary function(PF), degree of dyspnea, and SGRQ scores of patients in the observation group were significantly better than those of patients in the control group(P<0.05). Conclusion Acupoint application combined with Chinese medicine iontophoresis therapy can significantly improve the life quality of patients with COPD via improving PF and reducing the degree of dyspnea, which provides the further clinical application with significant effecacy.

天津市中医药管理局中医、中西医结合科研课题(13178)