目的 对唐古特白刺Nitraria tangutorum叶的化学成分进行研究。方法 采用溶剂萃取,反复硅胶柱色谱和制备液相色谱等方法进行分离纯化,根据理化性质及核磁数据鉴定化合物的结构。结果 从唐古特白刺叶的95%乙醇提取物中分离得到9个化合物,分别鉴定为4-氧代-β-紫罗兰醇-β-D-吡喃葡萄糖苷(1)、(6R,9R)-3-氧代-α-紫罗兰醇-β-D-吡喃葡萄糖苷(2)、blumenyl C β-D-glucopyranoside(3)、blumenyl A β-D-glucopyranoside(4)、丁香树脂酚-4'-O-β-D-吡喃葡萄糖苷(5)、citrusin B(6)、nikoenoside(7)、2-苯乙基-O-β-D-吡喃葡萄糖苷(8)和吲哚-3-乙基-β-D-吡喃葡萄糖苷(9)。结论 化合物1~9均为首次从该属植物中分离得到,其中,化合物9的¹³C-NMR数据为首次报道。

Objective To study the chemical constituents from the leaves of Nitraria tangutorum. Methods The chemical constituents were isolated by solvent extraction, repeated silica gel chromatography, and preparative-HPLC. Their structures were elucidated by physicochemical properties and ¹H-NMR and ¹³C-NMR data. Results Nine compounds were isolated from the ethanol extract of the leaves of N. tangutorum and their structures were identified as 4-oxo-β-ionol β-D-glycopyranoside(1),(6R, 9R)-3-oxo-α-ionol β-D-glycopyranoside(2), blumenyl C β-D-glucopyranoside(3), blumenyl A β-D-glucopyranoside(4), syringaresinol-4'-O-β-D-glucopyranoside(5), citrusin B(6), nikoenoside(7), 2-phenylethyl-β-D-glucopyranoside(8) and indole-3-ethyl-β-D-glucopyranoside(9). Conclusion All the isolates are reported from the plants of Nitraria L. for the first time and the ¹³C-NMR data of compound 9 are also reported for the first time.

国家自然基金联合项目(U1203104);青海省重大科技专项(2014-GX-A3A)