[关键词]
[摘要]
目的 研究乌药Lindera aggregata 根的化学成分。方法 应用硅胶、Sephadex LH-20 等多种色谱技术进行分离纯化,并利用波谱分析方法(MS,1D、2D-NMR)鉴定化合物结构。结果 从乌药根95%乙醇提取物中分离得到14 个化合物,其中化合物1为新化合物,命名为乌药双查耳酮(1),其余已知化合物分别鉴定为乌药环戊烯二酮甲醚(2)、乌药环戊烯二酮(3)、帕夏查耳酮(4)、球松素(5)、甲基赤芝酮(6)、松属素(7)、5,7-二羟基-6,8-二甲氧基黄酮(8)、赤芝酮(9)、乙基赤芝酮(10)、肉桂酸(11)、球松素查耳酮(12)、蓟黄素(13)和β-谷甾醇(14)。结论 化合物1为新化合物,化合物13为首次从该属植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from the roots of Lindera aggregata. Methods The compounds were isolated and purified by various column chromatographies. Their structures were elucidated by means of spectral analyses (MS, 1D-NMR, and 2D-NMR). Results Fourteen compounds were isolated from 95% ethanol extract of L. aggregate. Compound 1 was isolated as a new one and named as bi-linderachalcone (1), and the other compounds were identified as methyllinderone (2), linderone (3), pashanone (4), pinostrobin (5), methyllucidone (6), pinocembrin (7), 5,7-dihydroxy-6,8-dimethoxyflavone (8), lucidone (9), ethyllucidone (10), cinnamic acid (11), pinostrobinchalcone (12), cirsimaritin (13), and β-sitosterol (14), respectively. Conclusion Compound 1 is isolated as a new compound and compound 13 is firstly obtained from the plants of Lindera Thunb..
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[基金项目]
国家发改委"大规模综合性化合物库建设"专项基金