女贞子Ligustri Lucidi Fructus具有滋补肝肾作用,在古代用于骨痿等症的治疗,现代基础研究和临床研究也表明,女贞子在治疗骨质疏松方面有广阔的应用前景。通过查阅国内外相关文献,综述了关于女贞子治疗骨质疏松的相关实验研究和临床研究的进展,概括了女贞子和女贞子复方配伍治疗骨质疏松的作用机制,为进一步的实验研究和临床应用奠定了理论基础。

Ligustri Lucidi Fructus(LLF), which could nourish the liver and kidney, was used for the treatment of bone atrophy in ancient times.The current basic and clinical studies have shown that LLF had a broad application prospect in the treatment of osteoporosis.In this paper, by reviewing the related literature of home and abroad, we summarize the related experimental and clinical research progress of LLF and its compound on the treatment of osteoporosis, and clear their function mechanism, hoping to lay a theoretical foundation for further experimental study and clinical research.

国家自然科学基金资助项目(81273995,81274140),教育部和国家外专局高等学校学科创新引智计划资助项目(B07007)