[关键词]
[摘要]
目的 对金粟兰属植物及己Chloranthus serratus根乙醇提取物的化学成分进行研究。方法 利用多种色谱技术从及己根的氯仿萃取物中分离得到15个化合物。结果 通过理化性质和波谱数据鉴定其结构为1α,9α-二羟基-8,12-环氧桉叶-4,7,11-三烯-6-酮(1)、1β,5α-愈创木-4β,10α-二醇-6-酮(2)、zedoalactone A(3)、multistalactone C(4)、1β,8β-二羟基-桉叶-3,7(11)-二烯-8α,12-内酯(5)、1β,8β-二羟基-桉叶-4(15),7(11)-二烯-8α,12-内酯(6)、水合蒎醇(7)、伞形花内酯(8)、异嗪皮啶(9)、5-甲氧基-6,7-亚甲二氧基香豆素(10)、N-p-香豆酰酪胺(11)、N-反式-阿魏酰基酪胺(12)、N-顺式-阿魏酰基酪胺(13)、儿茶素(14)、7-羟基-5,8-二甲氧基二氢黄酮(15)。结论 化合物2、5~7、10、14、15为首次从金粟兰属植物中分离得到,化合物1、3、4为首次从该植物中分离得到。
[Key word]
[Abstract]
Objective To study chemical constituents contained in the ethanol extracts from the roots of Chloranthus serratus. Methods Fifteen compounds were separated from the roots of M. serratus by using various chromatographic techniques. Results Their structures were identified on the basis of physicochemical properties and spectral data as 1α,9α-dihydroxy-8,12-expoxy-eudesma-4,7,11-trien-6-one (1), 1β,5α-guaiane-4β,10α-diol-6-one (2), zedoalactone E (3), multistalactone C (4), 1β,8β-dihydroxy-eudesman-3,7(11)-dien-8α,12-olide (5), 1β,8β-dihydroxy-eudesman-4(15),7(11)-dien-8α,12 olide (6), sobrerol (7), umbelliferone (8), isofraxidin (9), 5-methoxy-6,7-methylene-dioxy coumarin (10), trans-N-p-coumaroyl tyramine (11), N-trans-feruloyl tyramin (12), N-cis-feruloyl tyramin (13), catechin (14), and 7-hydroxy-5,8-dimethoxyflavanone (15). Conclusion Compounds 2, 5—7, 10, 14 an 15 are obtained from the plants of Chloranthus Sw. for the first time, and compounds 1, 3, and 4 are isolated from C. serratus for the first time.
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[基金项目]
国家自然科学基金资助项目(21262019);江西省高等学校科技落地计划项目(KJLD13064)