[关键词]
[摘要]
目的 研究贵州虎皮楠Daphniphyllum oldhami枝叶中生物碱成分。方法 采用硅胶、Sephadex LH-20和RP18等柱色谱技术进行分离、纯化,通过MS、NMR等光谱学方法鉴定化合物的结构。结果 从虎皮楠枝叶中分离得到1个虎皮楠生物碱,命名为虎皮楠素D(1)。结论 化合物1为新的虎皮楠生物碱,该化合物结构中含有1个新颖的环戊二烯负离子结构单元。
[Key word]
[Abstract]
Objective To investigate the alkaloids of Daphniphyllum oldhami collected in Songtao of Guizhou province. Methods Column chromatographis including silica gel, Sephadex LH-20, and RP18 were used to isolate the alkaloid constituents, and their structures were elucidated by MS and NMR spectroscopic data. Results One alkaloid was obtained from D. oldhami and named as oldhamine D (1). Conclusion Compound 1 is a new Daphniphyllum alkaloid containing a rare cyclopentadienyl anion moiety.
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[基金项目]
国家自然科学基金资助项目(30830114,31100259,30800092,31360084,31360084)