有毒中药是中药重要组成部分,一直沿用至今,但有毒中药的监管及质量控制问题是影响中药安全性的关键问题,关系着中药现代化的进程。首先简述了有毒中药质量控制及其管理现状,就其药材基原、使用、炮制及质量控制等方面,讨论了有毒中药在研究与应用中存在的问题,阐述了制约有毒中药发展的原因,再结合药物质量控制及管理等方面内容,探讨关于有毒中药的合理应用,以期为有毒中药的应用发展提供有益参考。

The poisonous Chinese materia medica (CMM) has been used since the ancient period as an important part of the traditional Chinese medicine (TCM). However, the drug administration and quality control of poisonous CMM are the key issues which could affect drugs safety and play a crucial role with the modernization of TCM. This paper has reviewed the origins of drugs, using, processing methods, and quality control of poisonous CMM. The practical application in researching of poisonous CMM has also been analyzed, as well as its management problems. The restraints on the poisonous CMM development as well as the medicine quality control and management issues have been expounded, in order to provide the improvements of applying the poisonous CMM.

江西中医药大学校基金项目:基于"疗效-安全性"的已上市中西药复方制剂再评价示范研究(2013ZR0041)