[关键词]
[摘要]
目的 对江南紫金牛Ardisia faberi全草的化学成分进行分离、鉴定。方法 采用正相硅胶、D101大孔吸附树脂、MCI、Sephadex LH-20、C18、C8等柱色谱方法进行分离纯化,并运用波谱分析的方法鉴定化合物的结构。结果 从江南紫金牛全草80%乙醇渗漉液的醋酸乙酯部位和正丁醇部位分离得到11个化合物,分别鉴定为鲍尔烯醇(1)、油酸(2)、(Z)-10-heneicosenoic acid(3)、蚱蜢酮(4)、岩白菜素(5)、mallonanoside A(6)、没食子酸乙酯(7)、落新妇苷(8)、槲皮苷(9)、百两金皂苷B(10)、ardicrenin(11)。结论 化合物2、7、9、10、11是首次从该植物中分离得到,化合物3、4、6、8是首次从该属植物中分离得到。
[Key word]
[Abstract]
Objective To investigate the chemical constituents of Adisia faberi. Methods Compounds were isolated and purified by the normal phase silica gel, Sephadex LH-20, MCI gel, and ODS-A-HG packing material. Their structures were identified by the methods of MS, 1H-NMR, and 13C-NMR combined with physicochemical property. Results Eleven compounds were isolated and their structures were elucidateasbauerenol (1), oleic acid (2), (Z)-10-heneicosenoic acid (3), grasshopper ketone (4), bergenin (5), mallonanoside A (6), ethyl gallate (7), astilbin (8), quercitrin (9), ardisiacrispin B (10), and ardicrenin (11). Conclusion Compounds 2, 7, 9—11 are isolated from this plant for the first time; Compounds 3, 4, 6, and 8 are isolated from plants in genus Ardisia Swartz for the first time.
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[基金项目]
国家基础科学人才培养基金项目(J13100340-12);四川省科技厅省青年科技创新研究团队专项计划项目(2014TD0007);2014省级学术和技术带头人培养项目(003099013001)