[关键词]
[摘要]
目的 研究五味子Schisandra chinensis藤茎正丁醇部位的化学成分。方法 利用多种色谱分离技术进行分离纯化, 根据理化性质和波谱数据鉴定化合物的结构。结果 从五味子藤茎90%乙醇提取物的正丁醇部位中分离得到14个化合物, 分别鉴定为槲皮素(1)、槲皮素-3-O-β-D-吡喃葡萄糖苷(2)、槲皮素-3-O-β-D-吡喃木糖苷(3)、芦丁(4)、芹菜素(5)、芹菜素-7-O-β-D-吡喃葡萄糖苷(6)、异鼠李素-3-O-β-D-吡喃葡萄糖苷(7)、染料木素-7-O-β-D-吡喃葡萄糖苷(8)、绿原酸(9)、阿魏酸(10)、咖啡酸(11)、齐墩果酸(12)、儿茶素-7-O-β-D-吡喃葡萄糖苷(13)、胡萝卜苷(14)。结论 化合物3、7、8、13为首次从该植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents of n-butanol fraction from the stems of Schisandra chinensis. Methods The constituents were separated and purified by chromatographic technology, which structures were elucidated by physicochemical constants and spectral data analyses. Results Fourteen chemical constituents were isolated from the n-butanol extract in the stems of S. chinensis, and the structures were identified as quercertin (1), quercertin-3-O-β-D-glucopyranoside (2), quercetin-3-O-β-D- xylopyranoside (3), rutin (4), apigenin (5), apigenin-7-O-β-D-glucopyranoside (6), isorhamnetin-3-O-β-D-glucopyranoside (7), genistein-7-O-β-D-glucopyranoside (8), chlorogenic acid (9), ferulaic acid (10), caffeic acid (11), oleanolic acid (12), (+)-catechin-7- O-β-D-glucopyranoside (13), and daucosterol (14). Conclusion The compounds 3, 7, 8, and 13 are obtained from this plant for the first time.
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[基金项目]
吉林省重点科技攻关项目(20140204068YY, 20140204062YY);吉林省医药产业发展专项(YYZX201244, YYZX201286)