[关键词]
[摘要]
分子谱系地理学在药用植物遗传多样性、中药道地性形成机制以及中药核心种质构建中的应用研究是目前我国中药研究的热点.近年来,我国学者在中药资源领域深入到与DNA差异相关联的功能基因筛选和基因组学,已对甘草Glycyrrhiza uralensis、青蒿Artemisia caruifolia、丹参Salvia miltiorrhiza等多种药用植物功能基因开展了深入研究.基于分子谱系地理学的药用植物功能基因筛选及中药材基因组学研究将会是今后研究应用的主流.对近年来分子谱系地理学在中药分子鉴定和中药道地性形成机制,特别是药用植物功能基因筛选及基于此的基因组学方面研究进展进行综述.
[Key word]
[Abstract]
Phylogeography is a hot point in the field of Chinese materia medica (CMM) in the study on the genetic diversity of medicinal plants, geo-herbs formation mechanisms, and the construction of core collection. In recent years, the scholars in China studied the functional gene screening and the genomics associated with DNA differences in the field of CMM resources. And they have in-depth studied the functional genes of Glycyrrhiza uralensis, Artemisia annua, Salvia miltiorrhiza, and other medicinal plants. It will be the mainstream for functional gene screening of medicinal plants based on molecular phylogeography and geo-herbs genomics in the future researches and applications. In the paper, the authors review the recent progress in molecular phylogeography in the molecular identification of CMM, the formation mechanism of CMM genuineness, particularly the medicinal plant functional genes screening on which the genomic study is carried, and so on.
[中图分类号]
[基金项目]
湖北省自然科学基金项目——鄂西区域特色中草药药效物质基础研究与资源保护利用(2013CFA014);湖北省自然科学基金项目——基因条形码与药效相关联方法优化竹节参种质资源(2014CFB430)
