[关键词]
[摘要]
代谢组学是继基因组学、蛋白组学和转录组学之后出现的一门新兴的"组学",目前已在生命科学领域得到了广泛的应用并展现出良好的前景。代谢组学通过分析外界刺激后生物体内相对分子质量较低的代谢物的全面变化,来认识生物体的生理和病理状态。代谢组学为中药安全性评价,中药复方的物质基础与作用机制研究以及中医证候的认识提供了强有力的技术支持。
[Key word]
[Abstract]
Metabonomics is an emerging "omics" following genomics, proteomics, and transcriptomics. It has been widely used in the field of life science, and shows hopeful prospects. The principle of metabonomics is to understand the physiological and pathological state of the organism by comprehensive analysis of the metabolites with low relative molecular weight after external stimuli. In the present, metabonomics is widely used in the studies on traditional Chinese medicine (TCM), and provides the strong technical support for the TCM safety evaluation, the material basis and mechanism of Chinese medicinal formula, and understanding the recognition of TCM syndrome and sign.
[中图分类号]
[基金项目]
国家"973"项目课题(2013CB531801)