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[摘要]
目的 对黄杞Engelhardtia roxburghiana茎皮的化学成分进行研究.方法 采用多种柱色谱技术进行分离纯化,通过波谱分析鉴定化合物结构.结果 从黄杞茎皮90%乙醇提取物的醋酸乙酯萃取部分中分离得到10个化合物,分别鉴定为1β, 6α-二羟基桉烷-4(15)-烯(1)、(4S)-4-羟基-1-四氢萘酮(2)、(4S)-4, 8-二羟基-1-四氢萘酮(3)、对羟基苯甲酸(4)、山柰酚(5)、异甘草黄酮醇(6)、8, 3'-二异戊烯基山柰酚(7)、6, 5'-二异戊烯基槲皮素(8)、山柰酚-3-O-α-L-鼠李糖苷(9)、槲皮素-3-O-α-L-鼠李糖苷(10).结论 化合物1、4和6~8为首次在黄杞属植物中分离得到,首次从该属植物中分离得到异戊烯基取代黄酮.
[Key word]
[Abstract]
Objective To study the chemical constituents from the stem barks of Engelhardtia roxburghiana. Methods The compounds were isolated and purified by various chromatographic techniques and their structures were elucidated by spectral analysis. Results Ten compounds were obtained and identified as eudesm-4(15)-ene-1β, 6α-diol (1), (4S)-4-hydroxy-1-tetralone (2), (-)- regiolone (3), p-hydroxybenzoic acid (4), kaempferol (5), isolicoflavonol (6), broussoflavonol F (7), broussonol E (8), kaempferol-3-O- α-L-rhamnoside (9), and quercetin-3-O-α-L-rhamnoside (10). Conclusion Compounds 1, 4, and 6—8 are isolated from the plants of Engelhardtia Leschen. et Bl. for the first time, and the prenylated flavonoids are firstly reported in this genus.
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[基金项目]
科技基础性工作专项重点项目(2012FY110300);国家重点基础研究发展计划(2010CB951704);国家自然科学基金资助项目(31300293);云南省应用基础研究计划面上项目(2013FB067)