在中药现代化的研究过程中,指纹图谱技术是当今国际公认的控制中药质量的质控模式,但是如何实现中药指纹图谱数据的快速匹配、检索、识别和鉴定功能是指纹图谱研究中亟待解决的问题。中药指纹图谱数据库的研究和建立,为中药指纹图谱技术的推广和应用提供了一个有利的平台,有助于加快中药指纹图谱技术的研究和应用进程。主要从中药指纹图谱数据库研究历程、在中药现代化研究中的优势、研究成果等方面予以阐述。总结了中药指纹图谱数据库在中药现代研究中存在的问题,并展望了发展前景。

During the study of modernization of Chinese materia medica (CMM), the fingerprinting technology, as the model of the quality control of CMM, is gradually accepted by the world. But how to realize the fast matching, retrieval, recognition, and identification function of CMM fingerprint data is an urgent problem in the study of fingerprint. Studying and establishing CMM fingerprint database, which helps to speed up the study and application process of CMM fingerprinting technology, provides a favorable platform for the promotion and application of fingerprinting technology. This paper summarized the problems in the CMM fingerprint database research and prospected its bright future.

"重大新药创制"科技重大专项(2015ZX09501-006);江苏省科技支撑计划-工业项目(BE2012011);江苏省自然科学基金资助项目(BK20141093)