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[摘要]
西松烷型二萜类化合物是一大类结构新颖、特殊且具有重要生物活性的天然产物,目前分离得到的西松烷型二萜在结构上可分为异丙基型,五元、六元、七元、八元内酯环型,开环型,降碳型等类型,具有较好的细胞毒性和抗肿瘤活性。综述了2007年以来发现的193个新的西松烷类化合物的结构及生物活性,为进一步研究开发该类化合物提供依据。
[Key word]
[Abstract]
Cembranoid type diterpenes are important natural products which have novel structures and remarkable bioactivities. Cembranoid type diterpenes obtained now included isopropyl type, five, six, seven, eight membered lactone ring, open ring, reducing carbon types, etc, with cytotoxicity and antitumor activity. This paper reviews the structures and bioactivities of 193 cembranoid diterpenes which have been discovered since 2007, providing the scientific evidence for reasonable exploitation and application of cembranoid diterpenes.
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