[关键词]
[摘要]
目的 研究吴茱萸五加Acanthopanax evodiaefolius叶的化学成分。方法 采用硅胶柱色谱、凝胶柱色谱、制备薄层色谱及重结晶等方法进行分离纯化，利用波谱分析结合理化性质鉴定化合物的结构。结果 从吴茱萸五加叶甲醇提取物中分离得到13个化合物，分别鉴定为十七烷酸（1 ）、二十七烷醇（2 ）、反式肉桂酸（3 ）、乌苏酸（4 ）、齐墩果酸（5 ）、桦木酸（6 ）、科罗索酸（7 ）、芹菜素（8 ）、柚皮素（9 ）、麦芽酚（10 ）、丁香酸（11 ）、豆甾醇（12 ）、胡萝卜苷（13 ）。结论 化合物1～3、7～10 均为首次从本属植物中分离得到，所有化合物均为首次从吴茱萸五加中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from the leaves of Acanthopanax evodiaefolius. Methods The compounds were isolated and purified by silica gel and Sephadex LH-20 column chromatography. Their structures were identified on the basis of their physicochemical properties and spectroscopic data. Results Thirteen compounds were isolated from the methanol extract of A. evodiaefolius and their structures were identified as heptadecanoic acid (1 ), heptacosanol (2 ),trans-cinnamic acid (3 ), ursolic acid (4 ), oleanolic acid (5 ), betulinic acid (6 ), corosolic acid (7 ), apigenin (8 ), naringenin (9 ), maltol (10 ), syringic acid (11 ), stigmasterol (12 ), and daucosterol (13 ), respectively. Conclusion Compounds 1—3 and 7—10 are obtained from the plans in genus Acanthopanax Miq. for the first time and all the compounds are obtained from A. evodiaefolius for the first time.
[中图分类号]
[基金项目]
湖南省自然科学基金项目（11JJ2042）;湖南中医药大学药物分析学“十二五”校级重点学科建设项目（2012-2）;湖南省中药学重点学科建设项目
