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[摘要]
目的 对蕨麻Potentilla anserine块根的化学成分进行研究。方法 采用反复硅胶、Sephadex LH-20及ODS等柱色谱技术进行分离纯化,根据理化性质及波谱数据鉴定化合物的结构。结果 从蕨麻块根的石油醚和醋酸乙酯部位中分离得到13个化合物,分别鉴定为2, 19α-二羟基-3-羰基-1, 12-二烯-乌苏酸-28-O-β-D-葡萄糖苷(1 )、3β-O-乙酰坡模醇酸(2 )、3-表-2-氧代-坡模醇酸(3 )、2-氧代-坡模醇酸(4 )、坡模醇酸(5 )、野椿酸(6 )、arjunic acid(7 )、蕨麻苷B(8 )、2-氧代-坡模醇酸-28-O-β-D-葡萄糖苷(9 )、坡模醇酸-28-O-β-D-葡萄糖苷(10 )、刺梨苷(11 )、野蔷薇苷(12 )、腺嘌呤(13 )。结论 化合物1 为新的三萜皂苷,命名为蕨麻苷G,化合物3 和7 为首次从该属植物中分离得到,化合物1 和13 为首次从该植物中分离得到。
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[Abstract]
Objective To study the chemical constituents from the roots of Potentilla anserine. Methods The chemical constituents from the roots of P. anserine were isolated and purified by various chromatographic methods and their structures were elucidated on the basis of detailed spectroscopic analysis. Results Thirteen compounds were isolated from 75% ethanol extract of P. anserine and identified as 2, 19α-dihydroxy-3-oxours-1, 12-dien-28-oic acid 28-O-β-D-glucopyranosyl ester (1 ), 3β-acetoxy-19α-hydroxyursa-12-en-28-oic acid (2 ), 3-epi-2-oxopomolic acid (3 ), 2-oxopomolic acid (4 ), pomolic acid (5 ), euscaphic acid (6 ), arjunic acid (7 ), potentillanoside B (8 ), 2-oxopomolic acid 28-O-β-D-glucopyranoside (9 ), pomolic acid-28-O-β-D-glucopyranoside (10 ), kajiichigoside F1 (11 ), rosamultin (12 ), and adenine (13 ). Conclusion Compound 1 is a new triterpenoid saponin, named as potentillanoside G, compounds 3 and 7 are isolated from the plants of genus Potentilla L. for the first time, and compounds 1 and 13 are isolated from this plant for the first time.
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