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[摘要]
目的 观察坤泰胶囊对女性子宫切除术后围绝经期症状的影响。方法 收集125例因子宫良性病变而行子宫全切术的病例资料,分为治疗组和对照组。治疗组于术后1个月开始口服坤泰胶囊,每次4粒,3次/d;对照组术后一个月开始口服安慰剂,每次4粒,3次/d;两组术后避免使用任何影响卵巢功能的药物。服药3个月后对患者进行Kupperman评分,观察患者出现围绝经期的症状及时间,分别于服药前及服药3个月检测患者血清促卵泡激素(FSH)、雌二醇(E2)水平。结果 服药3个月后,治疗组围绝经期综合症的发病率低于对照组(P<0.05),雌激素水平治疗组高于对照组,差异有统计学意义(P<0.05)。结论 坤泰胶囊可有效改善子宫切除术患者围绝经期症状,值得临床推广。
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[Abstract]
Objective To find out the influence of Kuntai Capsule on ameliorating perimenopausal syndrome to women after hysterectomy. Methods Collecting 125 cases of hysterectomy due to uterine benign diseases, we divided them into Kuntai and control groups. The patients in the Kuntai group took Kuntai Capsule per os one month after the operation, the capsules were given at the dose of 4 tablets each time, t.i.d, and the patients in the control group took placebos, 4 tablets each time, t.i.d. Patients in both groups should avoid using any drugs that could influence the function of ovary. We tested the levels of follicle-stimulating hormone (FSH) and estradiol (E2) before and three months after the administration. Results After three months of administration, the incidence of perimenopausal syndrome in Kuntai group was lower than that in control group (P < 0.05), and the E2 level was higher in Kuntai group (P < 0.05). Conclusion Kuntai Capsule can improve the perimenopausal syndrome effectively.
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