[关键词]
[摘要]
目的 研究阿胶颗粒干法制粒的最佳工艺条件。方法 考察轧轮压力、轧轮转速和送粉速度对颗粒得率的影响,采用L9(34)正交试验优选阿胶颗粒干法制粒工艺条件。结果 最佳制粒工艺条件为轧辊压力为60~70 kgf/cm2、送粉速度17~19 r/min、轧轮转速为10~12 r/min。结论 阿胶颗粒干法制粒工艺的研究,为阿胶颗粒产业化应用和干法制粒技术在动物类中药中的推广应用提供实验依据。
[Key word]
[Abstract]
Objective To study the optimal technological conditions of Ejiao granules by dry granulation. Methods The effects of rolling wheel press, speed, and powder feeding rate on grain yield were studied, and the dry granulation technology for Ejiao granules was optimized using L9(34) orthogonal test. Results The optimal granulating conditions for the roll pressure was 60—70 kgf/cm2, powder feeding rate was 17—19 r/min, and rolling speed was 10—12 r/min. Conclusion The study on the dry granulation technology for Ejiao granules provides the experimental basis for industrial application and spread of dry granulation technology in Chinese animal medicines.
[中图分类号]
[基金项目]
重大新药创制科技重大专项“中药大品种阿胶技术改造”(2011ZX09201-201-10);山东省科技发展计划项目(2013G0031901)