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[摘要]
目的 研究黄花草木犀Melilotus officinalis的化学成分。方法 采用硅胶柱色谱、凝胶柱色谱和ODS柱色谱进行分离纯化,通过理化方法和波谱数据进行结构鉴定。结果 从黄花草木犀70%乙醇渗漉液中分离得到12个化合物,分别鉴定为β-谷甾醇(1)、香豆素(2)、对羟基苯丙酸甲酯(3)、山柰酚-3-O-α-L-鼠李糖苷(4)、芦丁(5)、芹菜素-7-O-β-D-芦丁糖苷(6)、邻苯二甲酸二丁酯(7)、robinin(8)、clovin(9)、山柰酚-3-O-芸香糖苷(10)、异槲皮苷(11)、美迪紫檀素-3-O-β-葡萄糖吡喃糖苷(12)。结论 化合物3、4、6、7、11、12为首次从该属植物中分离得到。
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[Abstract]
Objective To study the chemical constituents of Melilotus officinalis. Methods The compounds were isolated and purified by silica gel column chromatography, gel chromatography, and ODS column chromatography. Their structures were elucidated by chemical and spectral analyses. Results Twelve compounds were obtained from the 70% ethanol extract of M. officinalis and their structures were identified as β-sitosterol (1), coumarin (2), methyl 3-(4-hydroxyphenyl)propionate (3), kaempferol-3-O-α-L- rhamnoside (4), rutin (5), apigenin-7-O-β-D-lutinoside (6), dibutyl phthalate (7), robinin (8) clovin (9), kaempferol-3-O-rutinoside (10), isoquerecitrin (11), and medicarpin 3-O-β-glucopyranoside (12). Conclusion Compounds 3, 4, 6, 7, 11, and 12 are isolated from plants from Melilotus Miller for the first time.
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