目的 对拟缺香茶菜Isodon excisoides全草的化学成分进行研究。方法 采用多种柱色谱方法分离纯化，通过理化常数和光谱分析鉴定化合物的结构。结果 从拟缺香茶菜全草95%乙醇提取物中分离得到24个化合物，分别鉴定为(E)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-5-(4-hydroxyphenyl) pent-1-en-3-one（1）、2α, 3α, 24-三羟基-11-烯-乌苏-28, 13β-内酯（2）、腺花香茶菜素（3）、2α, 3α, 24-三羟基乌苏酸（4）、2α, 3α-二羟基乌苏酸（5）、2α, 3β, 24-三羟基乌苏酸（6）、3′, 4′, 5-三羟基-6, 7-二甲氧基黄酮（7）、2α, 3α-二羟基齐墩果酸（8）、2α, 3α, 24-三羟基齐墩果酸（9）、无羁萜（10）、尾叶香茶菜丙素（11）、鄂西香茶菜素（12）、大锥香茶菜甲素（13）、1α, 14β, 20-三羟基-7, 20-环氧-对映-贝壳杉-16-烯-15-酮（14）、肾形香茶菜丙素（15）、kamebacetal A（16）、木犀草素（17）、胡麻素（18）、熊果酸（19）、β-谷甾醇（20）、阿魏酸（21）、3, 4-二羟基桂皮醛（22）、3-吲哚甲醛（23）、十七烷酸（24）。结论 化合物1为新化合物，命名为拟缺香茶菜酮，化合物3～16及22～24为首次从该种植物中分离得到，化合物2为首次从该属植物中分离得到。

Objective To study the chemical constituents from Isodon excisoides. Methods Various column chromatographies were used in the isolation and purification, and the physicochemical constant determination and spectral analysis were adopted to identify the chemical structures. Results Twenty-four compounds were isolated and identified as (E)-5-hydroxy-1-(4-hydroxy-3- methoxyphenyl)-5-(4-hydroxyphenyl) pent-1-en-3-one (1), 2α, 3α, 24-trihydroxy-11-en-urs-28, 13β-olide (2), isodonadenanthin (3), 2α, 3α, 24-trihydroxy-12 (13)-en-urs-28-oic acid (4), 2α, 3α-dihydroxy-12 (13)-en-urs-28-oic acid (5), 2α, 3β, 24-trihydroxy-12-en- urs-28-oic acid (6), 3′, 4′, 5-trihydroxy-6, 7-dimethoxyflavone (7), 2α, 3α-dihydroxy-12-en-28-oic acid (8), 2α, 3α, 24-trihydroxy- 12-en-28-oic acid (9), friedelin (10), kamebakaurin (11), henryin (12), megathyrin A (13), ent-1α, 14β, 20-trihydroxy-7, 20-epoxy- kaur-16-en-15-one (14), reniformin C (15), kamebacetal A (16), luteolin (17), pedalitin (18), ursolic acid (19), β-sitosterol (20), ferulic acid (21), 3-(3, 4-dihydroxyphenyl)-prop-2-en-1-ol (22), indole-3-carboxaldehyde (23), and heptadecanoic acid (24). Conclusion Compounds 3—16 and 22—24 are firstly isolated from this plant, and compound 2 is isolated from the plants of Rabdosia (Bl.) Hassk. for the first time. Compound 1 is a new compound named excisoidone.