[关键词]
[摘要]
目的 对薄荷Mentha haplocalyx的化学成分进行研究。方法 采用多种柱色谱技术进行分离纯化,并通过波谱分析方法鉴定化合物的结构。结果 从薄荷乙醇提取物中分离得到了11个化合物,分别鉴定为薄荷木酚素(1)、5-羟基-6, 7, 8, 4′-四甲氧基黄酮(2)、桦木酸(3)、橙皮素-7-O-β-D-葡萄糖苷(4)、龙胆酸-5-O-β-D-(6′-水杨酰基)-葡萄糖苷(5)、蒙花苷(6)、刺槐素(7)、5-羟基-6, 7, 8, 3′, 4′-五甲氧基黄酮(8)、5, 6, 4′-三羟基-7, 8-二甲氧基黄酮(9)、田蓟苷(10)、藿香苷(11)。结论 化合物1为新的木酚素类化合物,命名为薄荷木酚素;化合物2为新天然产物;化合物4为首次从唇形科中分离得到;化合物3、5为首次从薄荷属中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from Mentha haplocalyx. Methods Compounds were isolated and purified by various chromatographic techniques, and their structures were identified by spectral analysis. Results Eleven compounds were isolated and identified, including menthalignin (1), 5-hydroxy-6, 7, 8, 4′-tetramethoxyflavone (2), betulinic acid (3), hesperetin 7-O-β-D-glucopyranoside (4), gentisic acid 5-O-β-D-(6′-salicylyl)-glucopyranoside (5), linarin (6), acatin (7), 5-hydroxy-6, 7, 8, 3′, 4′-pentamethoxyflavone (8), 5, 6, 4′-trihydroxy-7, 8-dimethoxyflavone (9), tilianin (10), and agastachoside (11). Conclusion Compound 1 is a new lignan named menthalignan; compound 2 is a new natural product; compound 4 is isolated from the plants in Labiatae for the first time, and compounds 3 and 5 are firstly reported in the plants of Mentha L.
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[基金项目]
国家“十二五”支撑计划项目(2011BA104B06)