目的 建立一种同时测定壮药剑叶龙血树中7-羟基-4′-甲氧基黄烷和紫檀茋的方法。方法 采用HPLC法，色谱柱为YMC pack ODS-AQ C₁₈（150 mm×4.6 mm，5 μm），乙腈-0.2%磷酸（36∶64）为流动相，检测波长分别为281、306 nm，柱温35 ℃。结果 7-羟基-4′-甲氧基黄烷、紫檀茋分别在0.407 6～1.528 5 μg（r＝0.999 8）、1.640 8～6.153 0 μg（r＝0.999 7）内呈良好的线性关系，平均加样回收率分别为97.88%、97.10%，RSD分别为0.82%、0.59%。结论 该方法操作简便、重复性好，可用于剑叶龙血树及其提取物的质量控制。

Objective To establish a method for the determination of 7-hydroxy-4′-methoxyflavane and pterostilbene in Zhuang Medicine Dracaena cochinchinensis. Methods The determination was developed on C₁₈ column. Acetonitrile-0.2% phosphoric acid (36 : 64) was used as mobile phase and the detective wavelength was set at 281 and 306 nm, respectively. Results The linear ranges of 7-hydroxy-4′-methoxyflavane and pterostilbene were 0.407 6—1.528 5 μg (r = 0.999 8) and 1.640 8—6.153 0 μg (r = 0.999 7), respectively. The average recovery was 97.88% (RSD = 0.82%) and 97.10% (RSD = 0.59%), respectively. Conclusion The method is simple and accurate, which could be used for the quality control of D. cochinchinensis and its extract.

广西科技攻关项目（桂科攻0630002-2M，10124000-15）；广西医药产业人才小高地资助项目（0802）