[关键词]
[摘要]
目的 研究尖瓣瑞香Daphne acutiloba茎中双黄烷酮类化学成分。方法 采用硅胶柱色谱与Sephadex LH-20凝胶柱色谱进行分离纯化,并运用波谱方法鉴定化合物的结构。结果 从尖瓣瑞香茎95%乙醇回流提取物醋酸乙酯萃取部位中分离得到14个双黄烷酮,分别鉴定为毛瑞香素A(1)、毛瑞香素C(2)、毛瑞香素C′(3)、毛瑞香素F(4)、毛瑞香素E(5)、荛花醇(6)、毛瑞香素K(7)、异狼毒素(8)、狼毒素(9)、毛瑞香素D1(10)、毛瑞香素H(11)、3-甲氧基-毛瑞香素H(12)、毛瑞香素K′(13)和毛瑞香素B(14)。结论 除化合物14外,其他化合物均为首次从该植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from the stems of Daphne acutiloba. Methods The constituents were separated by column chromatography and their structures were elucidated by spectral data analyses. Results Fourteen biflavans or biflavons were isolated from the EtOAc fraction of 95% ethanol reflux extract in the stems of D. acutiloba and were identified as daphnodorin A (1), daphnodorin C (2), daphnodorin C′ (3), daphnodorin F (4), daphnodorin E (5), wikstrol A (6), daphnodorin K (7), iso-chamaejasmin (8), (+)-chamaejasmin (9), daphnodorin D1 (10), daphnodorin H (11), 3-methoxyl daphnodorin H (12), daphnodorin K′ (13), and daphnodorin B (14). Conclusion All the compounds except 14 are obtained from the stems of this plant for the first time.
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[基金项目]
中央级公益性科研院所基本科研业务费(ITBB110301,1630052012014);海南省自然科学基金资助(211020)