[关键词]
[摘要]
目的 研究黄背栎Quercus pannosa的化学成分。方法 利用硅胶、RP18、高效液相等柱色谱技术对该植物进行分离和纯化,通过波谱和光谱数据鉴定化合物的结构。结果 从黄背栎95%乙醇浸出物醋酸乙酯萃取部位中分离得到8个化合物,其中4个木脂素类、4个三萜类化合物,分别鉴定为 (7α, 8β)-3-甲氧基-4′, 7-环氧-8, 3′-氧新木脂素-4, 9, 8′-三醇或 (7β, 8α)-3-甲氧基-4′, 7-环氧-8, 3′-氧新木脂素-4, 9, 8′-三醇(1)、(7α, 8β)-3-甲氧基-4′, 7-环氧-8, 3′-氧新木脂素-4, 9, 9′-三醇或 (7β, 8α)-3-甲氧基-4′, 7-环氧-8, 3′-氧新木脂素-4, 9, 9′-三醇(2)、(+)-丁香脂素(3)、(8R, 8′R)-4, 4′-二羟基-3, 3′-二甲氧基木脂素-7, 7′-二酮(4)、熊果酸(5)、齐墩果酸(6)、马斯里酸(7)、常春藤皂苷元(8)。结论 化合物1为新的木脂素类化合物,命名为黄背栎三醇;其他化合物均为首次从该植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents of Quercus pannosa. Methods The compounds were isolated and purified by chromatography on silica gel and RP C18 columns, and HPLC, and their structures were assigned on the basic of spectroscopic data. Results From the ethyl acetate fraction of 95% ethanol extract from Q. pannosa, eight compounds were isolated. Among them, four were lignans and other four were triterpenoids. They were identified as rel-(7α, 8β)-3-methoxy-4′, 7-epoxy-8, 3′-oxyneolignan-4, 9, 8′-triol (1), rel-(7α, 8β)-3-methoxy-4′, 7-epoxy-8, 3′-oxyneolignan-4, 9, 9′-triol (2), (+)-syringaresinol (3), (8R, 8′R)-4, 4′-dihydroxy-3, 3′-dimethoxylianane-7, 7′-dione (4), ursolic acid (5), oleanolic acid (6), maslinic acid (7), and hederagenin (8). Conclusion Compound 1 is a new lignan, named quercus pannosa-triol. The other compounds are isolated from this plant for the first time.
[中图分类号]
[基金项目]
国家自然科学基金资助项目(81021062,20902095)