目的 观察扶正消癥汤对肝癌介入治疗后血清前白蛋白（PA）水平的影响。方法 107例中晚期肝癌患者随机分成治疗组（59例）和对照组（48例），治疗组患者肿瘤动脉灌注化疗药物＋碘油栓塞＋口服扶正消癥汤，扶正消癥汤在进行肝动脉栓塞化疗术（TACE）前连续服用20 d；对照组患者除不口服扶正消癥汤外，其他治疗同治疗组，2组均给予TACE治疗4次。在TACE治疗前和治疗后3、10、25 d，分别测定2组患者血清PA水平的变化。结果 与对照组比较，治疗组患者在进行TACE治疗后第3、10天血清PA水平显著升高（P＜0.05）。结论 扶正消癥汤能有效地提高TACE术后血清PA的水平，促进肝功能恢复。

Objective To observe the effects of Fuzheng Xiaozheng Decoction (FXD) on serum prealbumin (PA) of patients with hepatocarcinoma after interventional therapy. Methods A total of 107 cases of patients with advanced hepatocarcinoma were divided into experimental (59 cases) and control (48 cases) groups. The patients in the experimental group were treated by arterial perfusion + lipiodol embolism + FXD (po), and before transcatheter arterial chemoemblization (TACE) FXD was given for 20 d. The patients in the control group were treated by TACE without FXD, and both groups were treated with TACE for four times. The levels of serum PA of the patients in each group were determined before the TACE and 3, 10, and 25 d after the TACE treatment, respectively. Results Compared with the control group, the serum PA levels of the patients in the experimental group 3 and 10 d after TACE treatment were increased obviously (P < 0.05). Conclusion FXD could effectively increase the level of serum PA after TACE treatment and promote the recovery of liver function.

浙江省金华市科技局资助项目（2005-1-323）