[关键词]
[摘要]
目的 研究莎草Cyperus rotundus根茎(香附)的化学成分。方法 采用硅胶、Sephadex LH-20等色谱方法对香附根茎中的化学成分进行分离纯化,应用谱学技术和化学方法鉴定化合物的结构。结果 从香附药材中分离得到10个化合物,分别鉴定为5, 7, 4′-三羟基-2′-甲氧基-3′-异戊烯基异黄酮(1)、6-O-p-hydroxybenzoyl-6-epi-aucubin(2)、6-O-p-hydroxy- benzoyl-6-epi-monomelittoside(3)、verproside(4)、syringopicroside B(5)、syringopicroside C(6)、oleuropeinic acid(7)、oleuroside(8)、10-hydroxyoleuropein(9)、senburiside I(10)。结论 化合物1为新化合物,命名为香附酮A,化合物2~10为首次从该植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical components from the rhizomes of Cyperus rotundus. Methods The compounds were isolated and purified by chromatographic techniques, and their structures were elucidated by spectral methods. Results A new isoflavonoid, 5, 7, 4′-trihydroxy-2′-methoxy-3′-prenylisoflavone (1), along with nine phenolic compounds, 6-O-p-hydroxybenzoyl- 6-epi-aucubin (2), 6-O-p-hydroxybenzoyl-6-epi-monomelittoside (3), verproside (4), syringopicroside B (5), syringopicroside C (6), oleuropeinic acid (7), oleuroside (8), 10-hydroxyoleuropein (9), and senburiside I (10), were obtained from the rhizomes of C. rotundus. Conclusion Compound 1 is a new isoflavone, named cyperotundone A, and compounds 2—10 are isolated from this plant for the first time.
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[基金项目]
广东高校优秀青年创新人才培养计划项目资助(2012LYM_0095);药用资源化学与药物分子工程教育部重点实验室科研项目(07109001-03);湛江市科技攻关计划非资助项目(2012C3102017);湛江师范学院自然科学研究项目博士专项(ZL1009)