目的 研究白子菜Gynura divaricata地上部分醋酸乙酯萃取部位的化学成分。方法 采用不同柱色谱技术进行分离纯化，结合MS和NMR数据进行结构鉴定。结果 从白子菜地上部分80%乙醇回流提取物的醋酸乙酯萃取部位中分离纯化得到14个化合物，分别鉴定为丁二酸（1）、丁二酸单甲酯（2）、丁二酸单乙酯（3）、丁二酸甲酯乙酯（4）、对羟基苯甲酸（5）、水杨酸（6）、异香草酸（7）、对香豆酸（8）、马栗树皮素（9）、槲皮素（10）、山柰酚（11）、异槲皮苷（12）、紫云英苷（13）、芦丁（14）。结论 化合物1～4、6～9为首次从该植物中分离得到。

Objective To study the chemical constituents of ethyl acetate fraction in 80% ethanol reflux extract from the aerial part of Gynura divaricata. Methods Column chromatographic techniques were applied to isolate and purify the chemical constituents. The chemical structures of the constituents were elucidated on the basis of mass properties and NMR spectral data. Results Fourteen compounds were isolated and their structures were determined spectroscopically as succinic acid (1), methyl succinate (2), ethyl succinate (3), ethyl methyl succinate (4), 4-hydroxybenzoic acid (5), salicylic acid (6), isovanillic acid (7), p-coumaric acid (8), esculetin (9), quercetin (10), kaempferol (11), isoquercitrin (12), astragalin (13), and rutin (14). Conclusion Compounds 1—4 and 6—9 are isolated from this plant for the first time.

国家自然科学基金青年基金项目（30900123）；江苏省科技基础设施建设计划—科技公共服务平台项目（BM2011117）