[关键词]
[摘要]
目的 研究头花蓼Polygonum capitatum地上部分的化学成分。方法 采用多种色谱技术进行分离纯化,根据理化性质和波谱数据鉴定其结构。结果 从头花蓼地上部分的70%乙醇提取物中分离得到25个化合物,分别鉴定为1-[(12E, 16E)-12, 16-二十碳二烯酰基]-2-[(E, E)-7, 11-十八碳二烯酰基]-3-硬脂酰基甘油(1)、24-亚甲基环阿尔廷醇(2)、植醇(3)、β-谷甾醇(4)、山柰酚(5)、原儿茶酸乙酯(6)、对羟基苯甲酸(7)、没食子酸乙酯(8)、5, 7-二羟基色原酮(9)、3-甲氧基槲皮素(10)、没食子酸(11)、N-反式咖啡酰酪氨酸(12)、β-胡萝卜苷(13)、槲皮苷(14)、山柰酚-3-O-α-L-吡喃鼠李糖苷(15)、山柰酚-3-O-β-D-吡喃葡萄糖苷(16)、2″-O-没食子酰基槲皮苷(17)、槲皮素(18)、2″-O-没食子酰基陆地棉苷(19)、杨梅苷(20)、短叶苏木酚酸乙酯(21)、短叶苏木酚(22)、槲皮素-3-O-(6″-O-反式阿魏酰基)-β-D-吡喃半乳糖苷(23)、酒渣碱(24)、鞣花酸(25)。结论 化合物1~3、7、12、21~25均为首次从该植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents in the aerial parts of Polygonum capitatum. Methods The chemical constituents were isolated and purified by various column chromatographic methods. Their chemical structures were identified by physicochemical properties and spectral analyses. Results Twenty-five compounds were isolated from the 70% ethanolic extract and identified as {1-[(12E, 16E)-12, 16-eicosadienoyl]-2-[(E, E)-7, 11-octadecadienoyl]-3-stearoylglycerol} (1), 24-methylenecyclo- artenol (2), phytol (3), β-sitosterol (4), kaempferol (5), ethyl protocatechuate (6), p-hydroxybenzoic acid (7), ethyl gallate (8), 5, 7-dihydroxychromone (9), 3-O-methylquercetin (10), gallic acid (11), N-trans-caffeoyltyramine (12), β-daucosterol (13), quercitrin (14), kaempferol-3-O-α-L-rhamnopyranoside (15), kaempferol-3-O-β-D-glucopyranoside (16), 2″-O-galloylquercitrin (17), quercetin (18), 2″-O-galloylhirsutrin (19), myricitrin (20), ethyl brevifolin carboxylate (21), brevifolin (22), quercetin-3-O-[(6″-O-trans- feruloyl)-β-D-galactopyranoside] (23), flazine (24), and ellagic acid (25), respectively. Conclusion Compounds 1—3, 7, 12, 21—25 are isolated from this plant for the first time.
[中图分类号]
[基金项目]