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[摘要]
目的 研究文冠果Xanthoceras sorbifolia花的化学成分。方法 采用制备薄层色谱、反复硅胶柱色谱、Sephadex LH-20柱色谱、ODS柱色谱等方法进行分离纯化,根据理化性质及光谱数据鉴定化合物的结构。结果 从文冠果花的70%乙醇提取物中分离得到8个化合物,分别鉴定为文冠果酮A(1)、山柰酚-3-O-α-L-吡喃鼠李糖苷(2)、3-O-甲基槲皮素(3)、山柰酚-3-O-β-D-吡喃葡萄糖苷(4)、异槲皮苷(5)、杨梅素-3-O-芸香糖苷(6)、酪醇(7)、异东莨菪素(8)。结论 化合物1为一新的单萜类化合物,并通过CD试验确定了绝对构型,化合物2~5、8为首次从文冠果属植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents in the flowers of Xanthoceras sorbifolia. Methods The constituents were isolated and purified by preparative TLC and silica gel, Sephadex LH-20, and ODS column chromatographies, and their structures were elucidated on the basis of their physicochemical properties and spectral data. Results Eight compounds were obtained and identified as xanthocerone A (1), kaempferol-3-O-α-L-rhamnopyranoside (2), 3-O-methyl-quercetin (3), kaempferol-3-O-β-D-glucopyranoside (4), isoquercitrin (5), myricetin-3-O-rutinoside (6), tyrosol (7), and isoscopoletin (8). Conclusion Compound 1 is a new monoterpenoid and its absolute configuration is determined by CD technique. Compounds 2—5 and 8 are isolated from the plants of Xanthoceras Bge. for the first time.
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[基金项目]
辽宁省博士启动基金资助(20081037)