[关键词]
[摘要]
目的研究翻白叶树Pterospermum heterophyllum根的化学成分。方法应用多种色谱技术进行分离纯化,根据理化性质和波谱数据鉴定化合物的结构。结果从翻白叶树根95%乙醇提取物中分离得到12个化合物,分别鉴定为莨菪苷(1)、2,6-二甲氧基-4-羟基-苯酚-1-O-β-D-吡喃葡萄糖苷(2)、3-甲氧基-4-羟基-苯酚-1-O-β-D-吡喃葡萄糖苷(3)、4-羟基-2-甲氧基-苯酚-1-O-β-D-吡喃葡萄糖苷(4)、甲基熊果苷(5)、(+)-南烛木树脂酚-3α-O-β-D-吡喃葡萄糖苷(6)、(-)-南烛木树脂酚-3α-O-β-D-吡喃葡萄糖苷(7)、(-)-南烛木树脂酚-2α-O-β-D-吡喃葡萄糖苷(8)、(-)-异落叶松树脂酚-6-O-β-D-吡喃葡萄糖苷(9)、(-)-8,8′-二甲氧基-开环异落叶松树脂酚-1-O-β-D-吡喃葡萄糖苷(10)、(+)-3-oxo-α-ionyl-O-β-D-glucopyranoside(11)、roseoside(12)。结论化合物1~11为首次从该属植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from the roots of Pterosperruuru heterop lluru. Methods The chemical constituents were isolated and purified by chromatographic techniques, and their structures were identified by physicochemical characteristics and spectroscopic analyses. Results Twelve compounds were isolated from the 95070 EtOH extract in the roots of heterophylluru and were identified as scopolin (1), 2, 6-dimethoxy-4-hydroxyphenol-l-O-p-D-glucopyranoside (2), 3-methoxy-4- hydroxyphenol-l-O-p-D-glucopyranoside (3), 4-hydroxy-2-methoxyphenol-l-O-p-D-glucopyranoside (4), methylarbutin (5),(+)- lyoniresinol-3a-O-p-D-glucopyranoside (6),(一)-lyoniresinol-3a-O-p-D-glucopyranoside (7),(一)-lyoniresinol-2a-O-p-D-glucopyranoside (8),(一)-isolariciresinol-6-O-p-D-glucopyranoside (9),(一)-8, 8'-dimethoxy-l-O-p-D-glucopyranosyl)secoisolariciresinol (10), (+)-3- oxo-a-ionyl-O-p-D-glucopyranoside (11), and roseoside (12). Conclusion Compounds 1一11 are isolated from the plants in Pterosperruuru Schreber for the first time.
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[基金项目]
国家科技重大专项“面向新药发现的数字化中药化学成分库”(2011ZX09307-002-01)