[关键词]
[摘要]
目的 研究岗梅Ilex asprella根的化学成分。方法 采用硅胶柱色谱、反相硅胶柱色谱等方法进行分离和纯化,并结合其理化性质及波谱数据鉴定化合物结构。结果 确定了12个化合物的结构,分别为乌索-12-烯-3β, 28-二醇, 3-乙酸酯(1)、β-谷甾醇(2)、赪酮甾醇(3)、28-nor-19βH, 20αH-ursa-12, 17-dien-3-ol(4)、randialic acid B(5)、19-去氢乌苏酸(6)、熊果酸(7)、坡模酸(8)、3-O-β-D-木糖基-3β-O-28-缺失-12, 17(18)-二烯乌苏烷(9)、β-胡萝卜苷(10)、冬青苷B(11)、赪酮甾醇-3-O-β-D-葡萄糖苷(12)。结论 化合物9为新化合物,命名为岗梅苷H。化合物1、2、4、7、8、10为首次从该植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents in the roots of Ilex asprella. Methods The chemical constituents were isolated by column chromatography on silica gel, RP silica gel, and so on. The structures were identified by spectral data and chemical methods. Results Twelve compounds were isolated and identified as uvaol aceta (1), β-sitosterol (2), clerosterol (3), 28-nor-19βH, 20αH-ursa-12, 17-dien-3-ol (4), randialic acid B (5), 19-dehydrouraolic acid (6), ursolic acid (7), pomolic acid (8), 3-O-β-D- xylopyranosyl-3β-O-28-nor-12, 17(18)-dien ursane (9), β-daucosterol (10), ilexoside B (11), and clerosterol-3-O-β-D-glucoside (12). Conclusion Compound 9 is a new compound named ilexasprellanoside H. Compounds 1, 2, 4, 7, 8, and 10 are obtained from this plant for the first time.
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[基金项目]
广东省科技计划项目(2010B060900073,2010B031900007);广东省教育部产学研结合项目(2011B090400191)