[关键词]
[摘要]
目的 对唇形科兔唇花属植物冬青叶兔唇花Lagochilus ilicifolius全草的化学成分进行研究。方法 运用多种色谱手段进行分离纯化,通过波谱解析进行结构鉴定。结果 从冬青叶兔唇花全草95%乙醇提取物中分离鉴定了10个化合物,分别为丁香脂素(1)、东莨菪素(2)、槲皮素(3)、杨梅素(4)、芦丁(5)、异槲皮苷(6)、山柰酚-3-O-芸香糖苷(7)、山柰酚-3-O-β-D-(6″-O-p-香豆素)葡萄糖苷(8)、8-O-乙酰基哈帕苷(9)、哈帕苷(10)。结论 首次从冬青叶兔唇花全草中分离鉴定了10个化合物,其中化合物1、7、8为首次从兔唇花属植物中分得。
[Key word]
[Abstract]
Objective To study the chemical components in the whole herb of Lagochilus ilicifolius. Methods The chemical components were isolated and purified by various column chromatographies and the structures were identified by spectral analysis. Results Ten compounds from the 95% ethanol extract were isolated and identified as (+)-syringaresinol (1), scopoletin (2), quercetin (3), myricetin (4), rutin (5), isoquercitrin (6), kaempferol-3-O-rutinoside (7), kaempferol-3-O-β-D-(6″-O-p-coumaryl) glycoside (8), 8-O-acetylharpagide (9), and harpagide (10), respectively. Conclusion Ten compounds are isolated from the whole herb of L. ilicifolius for the first time, among which compounds 1, 7, and 8 are isolated from the plants in genus Lagochilus Bunge for the first time.
[中图分类号]
[基金项目]
上海市科委西部计划专项(09405801700)