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[摘要]
目的 研究仙鹤草Agrimoniae Herba的化学成分。方法 利用硅胶柱色谱、大孔树脂柱色谱、Sephadex LH-20凝胶柱色谱进行反复分离纯化,根据化合物的理化性质和波谱数据鉴定其结构。结果 从仙鹤草中分离得到19个化合物,分别鉴定为β-谷甾醇(1)、三十二烷醇(2)、三十一烷醇(3)、十九烷酸(4)、十六烷酸(5)、二十烷酸(6)、二十七烷酸(7)、胡萝卜苷(8)、委陵菜酸(9)、银锻苷(10)、芹菜素-7-O-β-D-吡喃葡萄糖醛酸甲酯(11)、芹菜素-7-O-β-D-吡喃葡萄糖醛酸丁酯(12)、仙鹤草酚B(13)、汉黄芩素(14)、芹菜素(15)、山柰酚(16)、乌苏酸(17)、槲皮素(18)、异槲皮苷(19)。结论 化合物2~4、6、7、14均为首次从龙芽草属植物中获得。
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[Abstract]
Objective To investigate the chemical constituents of Agrimoniae Herba. Methods Repeated column chromatography with silical gel, maroporous resin column, and Sephadex LH-20 were used to isolate the chemical constituents, and their structures were elucidated on the physicochemical properties and basis of spectral data. Results Nineteen compounds were isolated and identified as β-sitosterol (1), dotriacontanol (2), hentriacontanol (3), nonadecanoic acid (4), palmitic acid (5), eicosanoic acid (6), heptacosanoic acid (7), daucosterol (8), tormentic acid (9), tiliroside (10), apigenin-7-O-methyl glucuronate (11), apigenin-7-O-butyl glucuronate (12), agrimophol B (13), wogonin (14), apigenin (15), kaempeferol (16), ursolic acid (17), quercetin (18), and isoquercitrin (19). Conclusion Compounds 2—4, 6, 7, and 14 are firstly obtained from the plants in Agrimonia L.
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