[关键词]
[摘要]
目的对水栀子Gardenia jasminoides var.radicans的化学成分进行研究。 方法采用色谱技术进行分离, 通过NMR等波谱方法鉴定化合物结构。 结果分离并鉴定了12个化合物, 其中3个为环烯醚萜苷类化合物, 分别为京尼平苷(1)、去乙酰车叶草苷酸甲酯(2)、6′-O-sinapoylgeniposide(3); 4个为二萜类化合物, 分别为西红花苷-1(4)、西红花酸(5)、西红花苷-2(6)、西红花苷-3(7); 4个为黄酮类化合物, 分别为芦丁(8)、5, 7, 3′, 5′-四羟基-6, 4′-二甲氧基黄酮(9)、5-羟基-7, 3′, 4′, 5′-四甲氧基黄酮(10)、麦黄酮(11);1个三萜类化合物为熊果酸(12)。 结论化合物2、3、5~12为首次从该植物中分离得到;化合物9和11为首次从该属植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents of Gardenia jasminoides var. radicans. Methods Some chromatographic methods were applied to isolating pure compounds and their structures were elucidated by spectroscopic methods. Results Twelve compounds were isolated and their structures were identified, including three iridoids:geniposide(1), deacetylasperulosidic acid methyl ester(2), and 6′-O-sinapoylgeniposide(3); four diterpenes: crocin-1(4), crocetin(5), crocin-2(6), and crocin-3(7); four flavonoids:rutin (8), 5, 7, 3′, 5′-tetrahydroxy-6,4′-dimethoxyflavone(9), 5-hydroxyl-7, 3′, 4′, 5′-tetramethoxyflavone(10), and tricin(11); one triterpene: ursolic acid(12). Conclusion Compounds 2, 3, and 5-12 are firstly isolated from this plant and compounds 9 and 11 are isolated from the plants of Gardenia Ellis for the first time.
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[基金项目]
广东省自然科学基金项目(9451052005001970);南药资源保护与利用工程技术开发中心项目(GCZX-B0905)