目的研究红葱Eleutherine americana的化学成分。方法采用硅胶柱色谱、Sephadex LH-20柱色谱及重结晶等方法, 分离纯化红葱的化学成分, 通过MS、NMR等波谱技术确定化合物结构。结果确定了7个化合物的结构, 分别为9-hydroxy-8-methoxy-1-methyl-1, 3-dihydronaphtho[2, 3-c]furan-4-O-β-D-glucopyranoside(1)、eleutherinoside A(2)、豆甾醇-3-O-β-D-葡萄糖苷(3)、kadsuric acid(4)、豆甾醇(5)、1, 2-二羟基-8-甲氧基-3-甲基蒽醌(6)、9-methoxy-1, 3-dimethyl-1H-naphtho[2, 3-c]pyran-5, 10-dione(7)。 结论化合物1为新化合物, 命名为红葱新苷。化合物3～5为首次从该植物中分离得到, 化合物6和7为首次获得的新天然产物。

Objective To investigate the chemical constituents from Eleutherine americana. Methods The chemical constituents were isolated and purified by column chromatography on silica gel, Sephadex LH-20, and recrystallization. Their structures were elucidated by means of MS and NMR. Results Seven compounds were isolated and identified as 9-hydroxy-8-methoxy-1-methyl-1, 3-dihydronaphtho [2, 3-c] furan-4-O-β-D-glucopyranoside (1), eleutherinoside A (2), stigmasterol-3-O-β-D-glucopyranoside (3), kadsuric acid (4), stigmasterol (5), 1, 2-dihydroxy-8-methoxy-3-methyl-anthra-9, 10-quinone (6), and 9-methoxy-1, 3-dimethyl-1H-naphtho [2,3-c] pyran-5, 10-dione (7). Conclusion Compound 1 is a new glucopyranoside named eleuthamoside; compounds 3-5 are isolated from the plant for the first time, and compounds 6 and 7 are two new natural constituents.